By Ph.D. Agarwal;Ms Srinivas Kamini A. Rao;Ashok

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Nature 1999;379:364-68. Yanagimachi R. Mammalian fertilization. In Knobil E, Neil JD, eds. The Physiology of Reproduction. New York: Raven Press 1994:189-317. Schatten G. The centrosome and its mode of inheritance: The reduction of the centrosome during gametogenesis and its restoration during fertilization. Dev Biol 1994;165:299-335. 3 Understanding the Physiology of Fertilization Ashok Agarwal, Andrew Luu ABSTRACT The growing trend of male factor infertility incidences, along with a decrease in sperm quality over recent years, is a cause for concern.

Birth defects in children conceived by ICSI compared with children conceived by other IVFmethods; a meta-analysis. Int J Epidemiol 2005;34(3):696701. 33. Moskovtsev SI, Willis J, White J, Mullen JB. Leukocytospermia: Relationship to sperm deoxyribonucleic acid integrity in patients evaluated for male factor infertility. Fertil Steril 2007;88(3):737-40. 34. Munoz-Garay C, De la Vega-Beltran JL, Delgado R, Labarca P, Felix R, Darszon A. Inwardly rectifying K+ channels in spermatogenic cells: Functional expression and implication in sperm capacitation.

Dev Biol 2001;234(1):261-74. 35. Nagy ZP, Joris H, Verheyen G, Tournaye H, Devroey P, Van Steirteghem AC. Correlation between motility of testicular spermatozoa, testicular histology and the outcome of intracytoplasmic sperm injection. Hum Reprod 1998;13(4):890-95. 36. Palermo GD, Neri QV, Takeuchi T, Hong SJ, Rosenwaks Z. Intracytoplasmic sperm injection: Technical aspects. In: Gardner DK, Weissman A, Howles CM, Shoham Z, editors. Textbook of Assisted Reproductive Technologies: Laboratory and Clinical Perspectives.

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